PHARMAWORLD

 PHARMACOKINETICS Pharmacokinetics is the study of how drugs move through the body, encompassing four key processes: absorption, distribution, metabolism, and excretion (ADME). Understanding these processes is crucial for optimizing drug administration and therapeutic effectiveness.   Key Processes in Pharmacokinetics Absorption : This is the process by which a drug enters the bloodstream from its site of administration. Factors influencing absorption include: Route of administration (oral, intravenous, etc.) Drug formulation and chemical properties Presence of food or other substances in the gastrointestinal tract Distribution : After absorption, the drug is distributed throughout the body. This phase is affected by: Blood flow to various tissues Lipophilicity (fat solubility) of the drug Molecular size and weight Binding to plasma proteins, which can affect the amount of free drug available for action Metabolism : This refers to the biochemical modification of the drug, prim...